BRAIN SUPPLEMENTS
At the Harmonized Brain Centers our passion is to help our clients achieve their Best Brain Ever by creating the best environment for the brain to operate. Our brain cells (neurons) speak in electrical and chemical activities and our brain supplements enhance the bio-chemical activity in all our cells. We recommend brain supplements / activators because it just makes sense. Our supplements are different in that they use the new field of nutritional health, nutrigenomics. Nutrigenomics is the "scientific study of the interaction of nutrition and genes, especially with regard to the prevention or treatment of disease. " Nutrigenomics activate our individual cells through supplementation so the body is actually producing what it needs. When it comes to brain optimization, our supplements activate our cells and can reduce oxidative stress, increase cellular energy (mitochondrial health), improve mood, cognitive function and increase overall health all through the use of natural scientifically formulated products.
Why Nrf2 Activation
Why we use Nrf2
What does stress (oxidative stress) have to do with brain function? You would be amazed! When we are in a stressed state especially for a prolonged period of time this state can negatively effect us physically, emotionally, cognitively, behaviorally and spiritually. Our brains just do not function well in a prolonged stressed state. Oxidative stress has been shown to be a leading theory of aging and deteriorating brain function. It is based on the fact that our cells are constantly bombarded by free radicals (we call the subsequent damage “oxidative stress”). Our bodies naturally produce antioxidants to fight oxidative stress, but our antioxidant production begins to decline in our early twenties. Protandim Nrf2 Synergizer was formulated to activate the Nrf2 pathway, a pathway responsible for antioxidant production. With peer-reviewed studies (see below) conducted by the likes of Harvard, Ohio State, the American Journal of Physiology and many more, Protandim Nrf2 Synergizer has been shown to reduce oxidative stress by 40% in just 30 days.*
Benefits
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Helps the body detoxify genes, keeping the master blueprint of the cell’s function intact *
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Reduces oxidative stress by 40% in just 30 days *
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Significantly reduces cellular stress through Nrf2 activation *
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Produces enzymes capable of neutralizing more than 1,000,000 free radicals *
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Helps to regulate survival genes *
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Supports the body's natural ability to repair and rejuvenate its own cells *
How to increase your energy through the Nrf1 pathway
Why Nrf1 Activation
"Why do I get so tired doing little things after my concussion? My concussion was not that bad." This is a common situation when someone has been concussed or been in a high stress situation for a long period of time. The Nrf1 pathway leads to the mitochondrial theory of aging and it is based on the fact that our mitochondria are literally powering everything in our bodies, from our heartbeat to our brain cells. Unfortunately, our mitochondria decline over time, when stressed or concussed. Protandim® NRF1 Synergizer is scientifically formulated to help your cells support mitochondrial function.*
Benefits
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Improves performance through energy function
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Enhances cellular health—cells function at peak performance
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Increases cellular energy (ATP)
Why Axio Drink Mix
Why Axio for the brain
Say no to energy drinks, say hello to Nootropics. AXIO takes a different approach to energy—specially formulated to give energy to your mind, not just your body. Because when you’re feeling tired or sluggish, it’s your brain that needs a pick-me-up, not your hyperactivity levels. Engineered with Nrf2 ingredients, AXIO is designed to wake your brain up, increase concentration, and deliver the right kind of energy, right when you need it without the jitters or caffeine crash. *
Benefits
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Improves mental endurance & mental acuity, concentration & memory retention*
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Enhances neurotransmitter function and the brain's resilience to stress*
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Reduces mental fatigue & brain fog*
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Increases physical & mental energy while improving positive mood*
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A clean, low-calorie, low-carb, vegetarian formula that is BSCG approved and free of artificial colors, artificial flavors and artificial sweeteners, GMOs and gluten.
Why NAD Activation?
Recently, scientists have been sharing the immense importance of proteins called sirtuins. Studies are showing sirtuin activity comes with a cascade of health benefits. Including supporting a healthy vascular system, maintaining cholesterol levels already in the healthy range, supporting the body’s healthy inflammatory response, supporting joint health, heightening mental focus, improving mood, motivation, energy, and much more. However sirtuin activity declines as we age (≃60%).
Sirtuin activation requires the molecule NAD. Protandim® NAD Synergizer was specifically formulated to target NAD, and has been shown to double sirtuin activity in 24 hours, supporting increased health, focus, energy, mental clarity, and mood. When combined with the Nrf1 and Nrf2 activators, we are seeing exponential benefits.
Benefits
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Supports healthy longevity *
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Supports autophagy (removal of cellular waste) *
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Improves mental focus and concentration *
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Supports positive mood and motivation *
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Boosts mental and physical energy *
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Supports body's healthy inflammatory response *
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Maintain cholesterol levels already in the healthy range *
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Supports healthy vascular system *
Other Research on Brain Supplements
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Fesharaki-Zadeh A.Int J Mol Sci. 2022 Oct 27;23(21):13000. doi: 10.3390/ijms232113000.PMID: 36361792 Free PMC article. Review.
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Traumatic Brain Injury (TBI) remains a major cause of disability worldwide. It involves a complex neurometabolic cascade, including oxidative stress. The products of this manuscript is examining the underlying pathophysiological mechanism, including re …
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Nrf2 deficiency induces oxidative stress and promotes RANKL-induced osteoclast differentiation.
Hyeon S, Lee H, Yang Y, Jeong W.Free Radic Biol Med. 2013 Dec;65:789-799. doi: 10.1016/j.freeradbiomed.2013.08.005. Epub 2013 Aug 14.PMID: 23954472
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Dunning S, Ur Rehman A, Tiebosch MH, Hannivoort RA, Haijer FW, Woudenberg J, van den Heuvel FA, Buist-Homan M, Faber KN, Moshage H.Biochim Biophys Acta. 2013 Dec;1832(12):2027-34. doi: 10.1016/j.bbadis.2013.07.008. Epub 2013 Jul 16.PMID: 23871839
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Synergistic induction of heme oxygenase-1 by the components of the antioxidant supplement Protandim.
Velmurugan K, Alam J, McCord JM, Pugazhenthi S.Free Radic Biol Med. 2009 Feb 1;46(3):430-40. doi: 10.1016/j.freeradbiomed.2008.10.050. Epub 2008 Nov 17.PMID: 19056485
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Sun C, Jin W, Shi H.Int J Mol Med. 2017 Jun;39(6):1548-1554. doi: 10.3892/ijmm.2017.2971. Epub 2017 Apr 27.PMID: 28487966
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The Endocannabinoid System and Oligodendrocytes in Health and Disease.
Ilyasov AA, Milligan CE, Pharr EP, Howlett AC.Front Neurosci. 2018 Oct 26;12:733. doi: 10.3389/fnins.2018.00733. eCollection 2018.PMID: 30416422 Free PMC article. Review.